The Cyber-Security Lab performs original researches on a variety of important topics including self-healing systems, trusted recovery, malware, intrusion detection and prevention systems, privacy protection in healthcare, network security, adversary models and game theory, and cyber defense situation awareness.

PIKE (Penn State Information, Knowledge, and Web) group studies various research issues including: data cleaning and mining, data privacy and security, XML data model and schema/query languages, web search, web services and semantic web, digital library, citation analysis and bibliometrics, and multimedia information system.

The Software Systems Security studies various research security issues in a wide spectrum of software systems.

The ALPS Lab conducts cutting-edge research on the intersection of machine learning, computational privacy, and cyber-security.